rehh: Searching for Footprints of Selection using 'Extended Haplotype Homozygosity' Based Tests

Population genetic data such as 'Single Nucleotide Polymorphisms' (SNPs) is often used to identify genomic regions that have been under recent natural or artificial selection and might provide clues about the molecular mechanisms of adaptation. One approach, the concept of an 'Extended Haplotype Homozygosity' (EHH), introduced by (Sabeti 2002) <doi:10.1038/nature01140>, has given rise to several statistics designed for whole genome scans. The package provides functions to compute three of these, namely: 'iHS' (Voight 2006) <doi:10.1371/journal.pbio.0040072> for detecting positive or 'Darwinian' selection within a single population as well as 'Rsb' (Tang 2007) <doi:10.1371/journal.pbio.0050171> and 'XP-EHH' (Sabeti 2007) <doi:10.1038/nature06250>, targeted at differential selection between two populations. Various plotting functions are included to facilitate visualization and interpretation of these statistics.

Version: 3.2.2
Depends: R (≥ 2.10)
Imports: methods,
Suggests: ape, bookdown, data.table, gap, knitr, qqman, rmarkdown, R.utils, testthat, vcfR
Published: 2021-09-15
DOI: 10.32614/CRAN.package.rehh
Author: Alexander Klassmann [aut, cre], Mathieu Gautier [aut], Renaud Vitalis [aut]
Maintainer: Alexander Klassmann <rehh at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
Citation: rehh citation info
Materials: NEWS
CRAN checks: rehh results


Reference manual: rehh.pdf
Vignettes: Examples in detail
Vignette for package *rehh*


Package source: rehh_3.2.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): rehh_3.2.2.tgz, r-oldrel (arm64): rehh_3.2.2.tgz, r-release (x86_64): rehh_3.2.2.tgz, r-oldrel (x86_64): rehh_3.2.2.tgz
Old sources: rehh archive

Reverse dependencies:

Reverse imports: coala


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