TransProR: Analysis and Visualization of Multi-Omics Data

A tool for comprehensive transcriptomic data analysis, with a focus on transcript-level data preprocessing, expression profiling, differential expression analysis, and functional enrichment. It enables researchers to identify key biological processes, disease biomarkers, and gene regulatory mechanisms. 'TransProR' is aimed at researchers and bioinformaticians working with RNA-Seq data, providing an intuitive framework for in-depth analysis and visualization of transcriptomic datasets. The package includes comprehensive documentation and usage examples to guide users through the entire analysis pipeline. The differential expression analysis methods incorporated in the package include 'limma' (Ritchie et al., 2015, <doi:10.1093/nar/gkv007>; Smyth, 2005, <doi:10.1007/0-387-29362-0_23>), 'edgeR' (Robinson et al., 2010, <doi:10.1093/bioinformatics/btp616>), 'DESeq2' (Love et al., 2014, <doi:10.1186/s13059-014-0550-8>), and Wilcoxon tests (Li et al., 2022, <doi:10.1186/s13059-022-02648-4>), providing flexible and robust approaches to RNA-Seq data analysis. For more information, refer to the package vignettes and related publications.

Version: 0.0.6
Depends: R (≥ 4.3.0)
Imports: magrittr, stats, data.table, dplyr, rlang, tibble, sva, DESeq2, edgeR, limma, ggplot2, ggVennDiagram, ggdensity, ggpubr, ggtree, hrbrthemes, grid, ggraph, tidygraph, tidyr, stringr, geomtextpath, ggalt, ggnewscale, ggtreeExtra, Hmisc, circlize, graphics, spiralize, ComplexHeatmap, grDevices
Suggests: prettydoc, knitr, rmarkdown
Published: 2024-12-10
DOI: 10.32614/CRAN.package.TransProR
Author: Dongyue Yu ORCID iD [aut, cre, cph]
Maintainer: Dongyue Yu <yudongyue at mail.nankai.edu.cn>
BugReports: https://github.com/SSSYDYSSS/TransProR/issues
License: MIT + file LICENSE
URL: https://github.com/SSSYDYSSS/TransProRBook
NeedsCompilation: no
Materials: README
CRAN checks: TransProR results

Documentation:

Reference manual: TransProR.pdf
Vignettes: TransProR (source)

Downloads:

Package source: TransProR_0.0.6.tar.gz
Windows binaries: r-devel: TransProR_0.0.6.zip, r-release: TransProR_0.0.6.zip, r-oldrel: TransProR_0.0.6.zip
macOS binaries: r-release (arm64): TransProR_0.0.6.tgz, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

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