CB2: CRISPR Pooled Screen Analysis using Beta-Binomial Test

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Version: 1.3.4
Depends: R (≥ 3.5.0)
Imports: Rcpp (≥ 0.12.16), metap, magrittr, dplyr, tibble, stringr, ggplot2, tidyr, glue, pheatmap, tools, readr, parallel, R.utils
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat, knitr, rmarkdown
Published: 2020-07-24
DOI: 10.32614/CRAN.package.CB2
Author: Hyun-Hwan Jeong [aut, cre]
Maintainer: Hyun-Hwan Jeong <jeong.hyunhwan at gmail.com>
License: MIT + file LICENSE
NeedsCompilation: yes
Materials: README
In views: Omics
CRAN checks: CB2 results


Reference manual: CB2.pdf
Vignettes: Handling the input matrix in CB2
CB2 Tutorial


Package source: CB2_1.3.4.tar.gz
Windows binaries: r-devel: CB2_1.3.4.zip, r-release: CB2_1.3.4.zip, r-oldrel: CB2_1.3.4.zip
macOS binaries: r-release (arm64): CB2_1.3.4.tgz, r-oldrel (arm64): CB2_1.3.4.tgz, r-release (x86_64): CB2_1.3.4.tgz, r-oldrel (x86_64): CB2_1.3.4.tgz
Old sources: CB2 archive


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